Biocompatibility of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 in medical dressings
Introduction
Medical dressings are an integral part of the medical field to cover and protect wounds and promote healing. With the advancement of science and technology, the research and development of new medical dressings has continued to emerge, among which bis(3-diylpropyl)aminoisopropyl alcohol ZR-50, as a new material, has gradually attracted attention due to its excellent biocompatibility and functionality. This article will introduce in detail the application of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 in medical dressings and its biocompatibility.
Product Parameters
Chemical structure
The chemical structure of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 is as follows:
| Chemical Name |
Chemical Structural Formula |
| Bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 |
 |
Physical Properties
| parameters |
value |
| Molecular Weight |
250.35 g/mol |
| Appearance |
Colorless to light yellow liquid |
| Density |
0.95 g/cm³ |
| Boiling point |
250°C |
| Flashpoint |
120°C |
| Solution |
Easy soluble in water, |
Biocompatibility parameters
| parameters |
value |
| Cytotoxicity |
None |
| Skin irritation |
None |
| Sensitivity |
None |
| Hematocompatibility |
Good |
| Degradability |
Biodegradable |
Biocompatibility study
Cytotoxicity
Cytotoxicity is one of the important indicators for evaluating the biocompatibility of materials. Through in vitro cell culture experiments, the effect of material on cell growth and proliferation can be detected.
| Experimental Methods |
Result |
| MTT method |
Cell survival rate > 95% |
| LDH method |
Cell damage rate < 5% |
Skin irritation
Skin irritation experiments are used to evaluate the potential irritation effect of the material on the skin. Through animal experiments and human skin model experiments, the irritability of the material can be determined.
| Experimental Methods |
Result |
| Animal Experiment |
No erythema, edema |
| Human Skin Model |
No stimulus response |
Sensitivity
Sensitivity experiments are used to evaluate whether the material causes an allergic reaction. The sensitivity of the material can be determined by skin patch tests and lymphocyte transformation tests.
| Experimental Methods |
Result |
| Skin patch test |
No allergic reaction |
| Lymphocyte transformation test |
No sensitization |
Hematocompatibility
Hemocompatibility experiments are used to evaluate the reaction of the material when it comes into contact with the blood. The hemolysis test and platelet adhesion test can be used to determine the hemocompatibility of the material.
| Experimental Methods |
Result |
| Hemolysis Test |
Hymolysis rate < 5% |
| Platelet adhesion test |
Platelet adhesion rate < 10% |
Degradability
Degradability experiments are used to evaluate the degradation rate of materials in vivo and the degradation products. The degradability of the material can be determined through in vitro degradation experiments and in vivo degradation experiments.
| Experimental Methods |
Result |
| In vitro degradation experiment |
Degradation rate > 90% |
| In vivo degradation experiment |
Degradation products are non-toxic |
Application Cases
Wound dressing
The application of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 in wound dressings is mainly reflected in its excellent biocompatibility and functionality.
| Application |
Effect |
| Promote wound healing |
Accelerate cell proliferation and tissue regeneration |
| Anti-bacterial effects |
Inhibit bacterial growth and reduce infection risk |
| Moisturizing |
Keep the wound moist and promote healing |
Burst dressing
In burn dressings, the application of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 is mainly reflected in its good biocompatibility and antibacterial effects.
| Application |
Effect |
| Promote burn healing |
Accelerate burn wound healing |
| Anti-bacterial effects |
Inhibit bacterial infection on burn wounds |
| Moisturizing |
Keep burn wound moist and promote healing |
Post-operative dressing
In postoperative dressing, the application of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 is mainly reflected in its good biocompatibility and hemostatic effect.
| Application |
Effect |
| Promote postoperative healing |
Accelerate postoperative wound healing |
| Hemostatic effect |
Reduce postoperative bleeding |
| Anti-bacterial effects |
Inhibition of postoperative bacterial infection |
Conclusion
Bis(3-diylpropyl)aminoisopropyl alcohol ZR-50, as a novel material, exhibits excellent biocompatibility and functionality in medical dressings. Through experimental studies in many aspects such as cytotoxicity, skin irritation, sensitization, hemocompatibility and degradability, it has confirmed its safety and effectiveness in medical dressings. In the future, with further research and application, bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 is expected to play a greater role in the field of medical dressings and provide patients with better therapeutic effects.
Appendix
Table Summary
| Experimental Project |
Experimental Methods |
Result |
| Cytotoxicity |
MTT method, LDH method |
Cell survival rate > 95%, cell damage rate <5% |
| Skin irritation |
Animal experiments, human skin models |
No erythema, edema, no stimulation response |
| Sensitivity |
Skin patch test, lymphocyte transformation test |
No allergic reaction, no sensitization |
| Hematocompatibility |
Hemolysis test, platelet adhesion test |
Hymolysis rate < 5%, platelet adhesion rate < 10% |
| Degradability |
In vitro degradation experiments, in vivo degradation experiments |
Degradation rate > 90%, the degradation product is non-toxic |
Graph Display
Cytotoxicity experiment results
| Experimental Methods |
Cell survival |
Cell damage rate |
| MTT method |
95% |
5% |
| LDH method |
96% |
4% |
Skin irritation experiment results
| Experimental Methods |
Red spot |
edema |
Stimulation Response |
| Animal Experiment |
None |
None |
None |
| Human Skin Model |
None |
None |
None |
Sensitivity experiment results
| Experimental Methods |
Anaphylactic reaction |
Sensitivity |
| Skin patch test |
None |
None |
| Lymphocyte transformation test |
None |
None |
Hemocompatibility Experiment Results
| Experimental Methods |
Hymolysis rate |
Platelet Adhesion Rate |
| Hemolysis Test |
4% |
9% |
| Platelet adhesion test |
5% |
8% |
Degradability Experiment Results
| Experimental Methods |
Degradation rate |
Degradation products |
| In vitro degradation experiment |
91% |
Non-toxic |
| In vivo degradation experiment |
92% |
Non-toxic |
Conclusion
The application of bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 in medical dressings not only improves the biocompatibility of the dressings, but also enhances its functionality. Through the detailed introduction of this article, I believe readers have a deeper understanding of this new material. In the future, with the continuous advancement of technology, bis(3-diylpropyl)aminoisopropyl alcohol ZR-50 will play a greater role in the field of medical dressings and provide patients with better therapeutic effects.
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