[Propylene glycol supply and procurement] Is propylene glycol allergic?

Propylene glycol is an organic compound (diol), usually slightly A sweet, odorless, colorless and transparent oily liquid that absorbs moisture and is easily mixed with water, acetone, and chloroform.

Is propylene glycol allergic?

In fact, the allergenicity of propylene glycol is not high, and the irritation of propylene glycol to the skin and mucous membranes in general dosage is actually very small. According to the supply of propylene glycol: Many water-based human lubricants on the market use propylene glycol and glycerin as key added ingredients to achieve moisturizing, thickening and other functions. In order to achieve a slimy feel, the propylene glycol content will be higher than that in wet wipes. These lubricant products for the most sensitive mucous membranes of the human body will not cause irritation or discomfort, so why worry about using wet wipes to wipe your hands?

Experiments have found that when propylene glycol has a concentration of 2%, only 0.2% (2/880) will produce allergic reactions, while at a concentration of 5% Allergic reactions were only 0.8% (27/3364). However, if the concentration is high (more than 5%) and it comes into repeated contact with the skin, there will be a strong possibility of causing allergies.

Generally, propylene glycol with a concentration of more than 5% seems to be mainly moisturizing products, and considering that moisturizing products are used more frequently, I am not interested in moisturizing products. Be careful when using propylene glycol. As for propylene glycol used as a solvent in other products, it itself is not too allergic, but because propylene glycol, like several other close relatives (such as glycerin), has the function of promoting penetration, it can help other ingredients penetrate into the skin. This feature is used In a good place, it can be used to develop drugs for skin injection to avoid the pain of shock, but in skin care products, it will increase the possibility of allergies caused by other ingredients. Therefore, we are careful about the possibility of allergy to propylene glycol in moisturizing products, while in other categories of products we are worried about other possible allergies.

Therefore, we must be careful about the possibility of allergies to propylene glycol in moisturizing products, and in other categories of products, we must worry about other allergic ingredients causing allergies with propylene glycol, because Many ingredients have the effect of promoting penetration. Even if you abandon propylene glycol, it does not mean that you will be foolproof. Especially users who use a lot of products should pay more attention. Maybe the products you usually use do not cause you to be allergic, but combined with other products Allergic reactions may occur after penetration enhancers such as propylene glycol are contained in the product. Instead of just focusing on propylene glycol, the real culprit is missed.