Chelidonerythrine products have not yet been commercially produced and have good market prospects in the future.

Cheerythrine (CHE) is an isoquinine-type benzophenanthridine alkaloid isolated from plants such as celandine, leucophylla, and bloodweed. It has anti-tumor, anti-inflammatory, and antibacterial effects. . As a plant extract, the purity of crude chelerythrine is between 40% and 60%, and the toxicity of high-purity products can reach 98% and above.

Chelidonine can be extracted from plants of the Papaveraceae and Rutaceae families, such as celandine, Bospermia spp., Saccharomyces cerevisiae, Acanthus cerevisiae, Acupuncture unilateralis, Hematospermum sibiricum, Coptidis chinensis, etc. Wild resources are abundant. Chedyronine can be used in the fields of medicine, pesticides, feed additives, etc., and my country is a major consumer of medicine, pesticides, and feed additives, so the potential application market of chelerythrine is good.

According to the“China Chelidonerythrine Industry Market Supply and Demand Status and Development Trend Forecast Report 2023-2027” released by the Industrial Research Center It shows that although my country is rich in wild resources of chelerythrine and research on chelerythrine has made some progress at home and abroad, the commercial production of chelerythrine has not yet been achieved in my country, mainly because of the Phytoerythrine products are relatively niche, and separation, extraction and purification technology is difficult to achieve; currently, only a few companies on the market produce Boluohui extract (the main ingredients are chelerythrine and sanguinarine).

At present, my country has not yet realized the production of chelerythrine. The products of the same nature circulating in the market are mainly Boluohui extract, including Boluohui original powder and Boluohui powder. Domestic Boluohuisan manufacturers include Hunan Hanqing Biotechnology Co., Ltd., Hunan Huakang Biotechnology Co., Ltd., Hunan Meike Bioresources Co., Ltd., etc. In addition to meeting the domestic market demand, the products are also exported to EU countries. .

As an alkaloid that widely exists in natural plants, chelerythrine’s anti-inflammatory, antibacterial, antiviral and other biological activities are being widely used in animal husbandry, agriculture, aquaculture and other fields. Research on alkali extraction and separation, pharmacological activity, mechanism of action, and preparation of new dosage forms is also increasingly in-depth, but further exploration is still needed in the medical field. Currently, there are many studies on the treatment of tumors with chelerythrine, such as research on chelerythrine in adenoid cystic carcinoma, new coronavirus and other diseases.

It is expected that from 2023 to 2028, with the continued development of the domestic chelerythrine industry, the product may be produced in small batches and applied to pesticides, feed and other fields. However, due to the small overall market size of the domestic chelerythrine industry, it will take some time to expand the downstream application areas; therefore, in the short term, the domestic chelerythrine import business volume will be very small.

Industrial researchers believe that in recent years, as life pressure has increased and life has become irregular, the number of people suffering from cancer in our country has continued to increase. Dryerythrine can participate in the regulation of cell apoptosis and cell cycle, and may play a role in cancer treatment. Investors can pay attention to research and development and reports in this area.