Downstream growth momentum is strong, 3-bromo-1-(3-chloro-2-pyridyl)-1H-pyrazole-5-carboxylic acid (K acid) market has huge room for development

There are three synthesis methods for chlorantraniliprole. The main synthesis method is the amidation reaction of pyrazole compounds and anthranilic compounds. Pyrazole compounds are mainly 3-bromo-1-(3-chloro-2-pyridyl)-1H-pyrazole-5-carboxylic acid (K acid). As one of the key intermediates of chlorantraniliprole, in recent years In recent years, with the expansion of chlorantraniliprole production capacity, the market demand for K acid has been rapidly released.

Chlorantraniliprole is a new type of insecticide with multiple advantages such as broad spectrum, high efficiency, low toxicity, long duration of effect and strong penetration. Chlorantraniliprole is the bisamide insecticide with the largest market share, accounting for about 70%. The chlorantraniliprole market has strong growth momentum, with global market sales of approximately US$2.45 billion in 2022.

my country is a big agricultural country, and there is a vast space for the development of chlorantraniliprole. As the patent of the compound expires, many companies including Runfeng Co., Ltd., Hailier, Lier Chemical, Yangnong Chemical, Youdao Chemical, etc. are vying to deploy chlorantraniliprole. Benzamide technical and intermediate industrial chain. Since 2020, the total declared production capacity of chlorantraniliprole has reached about 100,000 tons. The increase in chlorantraniliprole-related production capacity will inevitably drive the release of market demand for key upstream intermediates K acid and K amine, and there is considerable room for incremental market demand.

In addition to chlorantraniliprole, K acid is also an important intermediate for pesticides such as cyantraniliprole and cyantraniliprole. Since the patent of the compound has not expired (February 2025), the domestic market for bromantraniliprole is currently blank. However, as a new broad-spectrum pesticide, the market development space for bromantraniliprole is broad. In the future, as the patent expires, the market for bromantraniliprole in my country will The scale of the insecticide industry will expand. Cyantraniliprole was developed by DuPont in the United States. Currently, relevant manufacturers include Bayer, Combinatorial Chemicals, Sumitomo Chemical, Japan Soda, etc. Thanks to the registration and launch of new products and compound products, the global cyantraniliprole market is in a growth trend as a whole. .

According to the “2023-2028 3-bromo-1-(3-chloro-2-pyridyl)-1H-pyrazole-5- released by the Industrial Research Center Carboxylic acid (K acid) industry market in-depth research and investment prospect forecast analysis report” shows that with the expansion of production capacity of pesticides such as chlorantraniliprole, cyantraniliprole, and cyantraniliprole, , the market demand for K acid will be further released, and the industry has broad prospects for development. Domestic K-acid suppliers include Nanjing Red Sun Co., Ltd., Kangtai Chemical Co., Ltd., Yufu Biotechnology Co., Ltd., etc. Thanks to strong downstream demand, the scale of the K-acid industry is expected to further expand.

In 2021, the China Pesticide Industry Association plans to formulate the first batch of CCPIA group standard projects, including sodium acetate by-product of K acid, potassium sulfate by-product of K acid, sodium sulfate by-product of K acid, and sodium chloride by-product of K acid Four items of salt. The traditional production process of K-acid has a long synthesis process, low yield, and complex by-product salt components that are difficult to handle. As environmental protection supervision becomes increasingly strict, the market is demanding new, environmentally friendly, efficient, and low-cost K-acid preparation processes.

In September 2023, the China Pesticide Industry Association issued a call for applications for “3-bromo-1-(3-chloro-2-pyridyl)-1H-pyrazole-5-carboxylic acid (K “Acid) Green Synthesis Technology” Announcement. Industry analysts said that under this background, the K acid industry will continue to move towards standardization, greenness, efficiency and standardization. In the future, enterprises with green synthesis technology, excellent product performance, and low-cost mass supply will have greater development potential.