PQQ (pyrroloquinoline quinone) has rich functions and industry development opportunities and challenges.

PQQ, pyrroloquinoline quinone, is an oxidoreductase prosthetic group with the molecular formula C14H6N2O8. It is the third prosthetic group found in membrane-bound bacterial dehydrogenases after flavin nucleotides and nicotinamide nucleotides. . PQQ is widely found in soil, microorganisms, plants and animal tissues, including breast milk, green peppers, kiwi fruit, tea, papaya, spinach, celery, soybeans, broccoli, grapefruit, etc.

PQQ is called the fourteenth vitamin. It is a kind of chemical substance with various functions and application values. PQQ has super antioxidant ability, which can protect mitochondria from oxidative damage, protect myocardial cells from ischemia-reperfusion injury, etc.; it can improve the redox capacity of cells, help the body resist fatigue, and improve concentration and memory, etc.; It can remove ROS, has anti-inflammatory effects and enhances the body’s immune regulation ability; can improve neuron damage and has neuroprotective effects.

PQQ has powerful effects and rich functions. It has become an important raw material needed in health food, energy drinks, dietary supplements, health products, animal feed, medicine, cosmetics and other fields. Currently, against the background of the continuous strengthening of national health awareness and the continuous upgrading of consumer demand, the market demand for PQQ continues to increase, and the industry is ushering in a period of development opportunities. But at the same time, the development of the PQQ industry is also restricted by low market awareness. Compared with other functional raw materials, hyaluronic acid and collagen, PQQ is still relatively unknown in the consumer market. In the future, companies will need to continue to strengthen product promotion. , the industry has huge room for growth.

According to the“China PQQ (Pyrroloquinoline Quinone) Industry Market Monitoring and Future Development Prospects Research Report 2023-2027” released by the Industrial Research Center 》 It is shown that there are two main production methods of PQQ, namely chemical synthesis method, which has the advantages of easy availability of raw materials, low cost, controllable reaction, high production efficiency, long reaction route and serious environmental pollution. The microbial fermentation synthesis method has the advantages of controllable production process, reusable bacterial strains, low environmental pollution, and high production safety, as well as the disadvantages of difficulty in obtaining bacterial strains, low reaction efficiency, and high separation costs.

Among them, microbial fermentation synthesis is currently a common method used by domestic companies to produce PQQ. Representative companies include Fujian Ubaifu Biotechnology, Fuzhou Kangtai Biotechnology, Shandong Jincheng Pharmaceutical, Zhejiang Pharmaceutical Co., Ltd., Shenzhen Kangtai Biological Products, and Hubei Meiqi Health Technology. etc.; the representative enterprise that uses chemical synthesis to produce PQQ is Zhucheng Haotian Pharmaceutical.

Industry analysts said that PQQ is a new type of enzyme prosthetic group with powerful effects and rich functions. It has been widely used in the fields of food, medicine, cosmetics, health products, dietary supplements and other fields. Currently, as the national health awareness continues to strengthen, its market demand continues to increase, and there is broad room for development in the market. However, due to low awareness, my country’s PQQ market is still underdeveloped. In the future, local companies will need to continue to strengthen product promotion and expand market development space.