Analysis of active ingredients of bis-(2-dimethylaminoethyl) ether in medical device disinfectant

1. Introduction

Medical device disinfectant is an indispensable part of the medical industry and is used to ensure the sterile state of medical devices before use. As an important active ingredient, bis-(2-dimethylaminoethyl) ether (hereinafter referred to as “bis-ether”) has gradually increased in recent years. This article will conduct a detailed analysis of the active ingredients of bis ethers in medical device disinfectants, including their chemical properties, mechanism of action, product parameters, application effects, etc., aiming to provide a comprehensive reference for relevant practitioners.

2. Chemical properties of bis-(2-dimethylaminoethyl) ether

2.1 Chemical structure

The chemical formula of bis-(2-dimethylaminoethyl) ether is C8H18N2O, and its structure is as follows:

 CH3
    |
CH3-N-CH2-CH2-O-CH2-CH2-CH2-N-CH3
    |
   CH3

2.2 Physical Properties

2.3 Chemical Properties

Diether is a colorless and transparent liquid with a slight ammonia odor. It is stable at room temperature, but may decompose under high temperature or strong acid and alkali conditions. Bis ethers are highly alkaline and can react with acid to form salts.

3. Mechanism of action of bis-(2-dimethylaminoethyl) ether

3.1 Disinfection principle

Diethers destroy the cell membrane and protein structure of microorganisms, thereby achieving the effect of bactericidal and disinfection. Its mechanism of action mainly includes the following aspects:

1. Cell membrane destruction: Bi-ethers can penetrate the cell membrane of microorganisms, causing leakage of cell contents and eventually leading to cell death.
2. Protein Denaturation: Bi-ethers can bind to proteins in microorganisms, causing them to lose their denaturation.to inhibit the growth and reproduction of microorganisms.
3. Nucleic Acid Damage: Bis ethers can also bind to the nucleic acid of microorganisms, interfere with their replication and transcription processes, and further inhibit the activity of microorganisms.

3.2 Antibacterial spectrum

Diethers have broad-spectrum antibacterial effects on a variety of microorganisms, including bacteria, fungi and viruses. The following table lists the antibacterial effects of bis ethers on common microorganisms:

4. Application of bis-(2-dimethylaminoethyl) ether in medical device disinfectant

4.1 Product parameters

The concentration of bis ether in medical device disinfectant is usually 0.1%-1.0%. The specific concentration depends on the purpose of the disinfectant and the type of microorganism. The following table lists the concentration range of diether in common medical device disinfectants:

4.2 Application Effect

Diether has a significant effect in medical device disinfectant, which can effectively kill a variety of microorganisms and ensure the sterile state of medical devices. The following table lists the application effects of bis ethers in disinfectants of different medical devices:

4.3 Precautions for use

1. Concentration Control: The concentration of bis ether may cause corrosion of medical devices, and too low may affect the disinfection effect, so the concentration needs to be strictly controlled.
2. Usage time: The soaking time of the disinfectant should be adjusted according to the type of medical devices and the degree of contamination, usually 10-30 minutes.
3. Storage conditions: Diether disinfectant should be stored in a cool and dry place to avoid direct sunlight and high temperatures.

5. Safety of bis-(2-dimethylaminoethyl) ether

5.1 Toxicity Assessment

Diesel ethers are relatively safe for the human body at low concentrations, but may have an irritating effect on the skin and mucosa at high concentrations. The following table lists the results of toxicity assessment of bis ethers:

5.2 Safe use suggestions

1. Personal Protection: When using bisexual disinfectant, you should wear gloves, masks and goggles to avoid direct contact with the skin and eyes.
2. Ventiation Conditions: When using bis-ether disinfectant, ensure that the operating environment is well ventilated and avoid inhaling high-concentration steam.
3. Emergency treatment: If you accidentally contact the bis ether disinfectant, you should immediately rinse with a lot of clean water and seek medical help.

6. Environmental impact of bis-(2-dimethylaminoethyl) ether

6.1 Biodegradability

Diesel ethers have certain biological organisms in the environmentDegradability, but its degradation rate is slower. The following table lists the results of the biodegradability assessment of bis ethers:

6.2 Environmental Impact Assessment

The residue of bis ethers in the environment may have a certain impact on aquatic organisms, so environmental protection should be paid attention to when using and discharging. The following table lists the results of the environmental impact assessment of bis ethers:

7. Future development of bis-(2-dimethylaminoethyl) ether

7.1 New disinfectant development

With the continuous development of medical technology, the requirements for medical device disinfectants are becoming higher and higher. In the future, bis ethers may be combined with other active ingredients to develop more efficient and safe disinfectants.

7.2 Green and environmental protection trend

In the context of increasing environmental awareness, green and environmentally friendly disinfectants of bisexual ethers will become the focus of future development. By improving production processes and formulations, the negative impact of bis ethers on the environment is reduced.

7.3 Intelligent Application

With the popularization of intelligent technology, the application of bisexual disinfectant will also be more intelligent. For example, the concentration and effect of disinfectant is monitored in real time by sensors to ensure the sterile state of medical devices.

8. Conclusion

Bis-(2-dimethylaminoethyl)ether, as an important active ingredient, has wide application prospects in medical device disinfectants. Through a comprehensive analysis of its chemical properties, mechanism of action, product parameters, application effects, safety and environmental impact, we can better understand and utilize this ingredient to provide more efficient and safe solutions for the disinfection of medical devices. In the future, with the continuous advancement of technology, the application of bis ether in medical device disinfectants will become more extensive and in-depth.

AttachedRecord: FAQ

Q1: What are the storage conditions for bis-(2-dimethylaminoethyl) ether?

A1: Diethers should be stored in a cool and dry place to avoid direct sunlight and high temperatures. The recommended storage temperature is 15-25°C.

Q2: What is the disinfection effect of bis-(2-dimethylaminoethyl) ether?

A2: Bi-ethers have broad-spectrum antibacterial effects on a variety of microorganisms, including bacteria, fungi and viruses. Its disinfection effect is significant and can effectively kill a variety of microorganisms.

Q3: How safe is bis-(2-dimethylaminoethyl) ether?

A3: Bis ethers are relatively safe for the human body at low concentrations, but may have an irritating effect on the skin and mucosa at high concentrations. Personal protective equipment must be worn during use and ensure good ventilation in the operating environment.

Q4: What is the impact of bis-(2-dimethylaminoethyl) ether on the environment?

A4: Bis ethers have certain biodegradability in the environment, but their degradation rate is slow. Residues in the environment may have a certain impact on aquatic organisms, so environmental protection should be paid attention to when using and discharging.

Table summary

Through the detailed analysis of this article, I believe that readers have a deeper understanding of the active ingredients of bis-(2-dimethylaminoethyl) ether in medical device disinfectant. I hope this article can provide valuable reference for relevant practitioners and promote the further development of medical device disinfectant technology.

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