Magnesium stearate is white loose fine powder, smooth to the touch, insoluble in water, ethanol and ether, soluble in hot water and ether, and decomposes into stearic acid when exposed to acid. and the corresponding magnesium salts. The solubility in room temperature water is 77-79 mg/L, and it is soluble in hot ethanol. It has a slight odor and a greasy feel.
Magnesium stearate can be used as lubricant and excipient in medicine:
Magnesium stearate pharmaceutical tablet raw material (excipient, Lubricants) are new pharmaceutical excipients that can be used as film-forming coating materials for solid preparations, thickeners, and suspensions for colloidal liquid preparations.
Magnesium stearate is the most common ingredient used to form tablets because it is an amazing lubricant. Known as a “flow agent,” it helps speed up the manufacturing process because it prevents ingredients from sticking to mechanical equipment. Only a negligible amount of the powder mixture is needed to coat almost any medication or supplement mixture.
Not only does magnesium stearate transport smoothly on the machines that make the pills, it also makes the pills easier to swallow and move down the gastrointestinal tract. Magnesium stearate is also a common excipient, which means that it helps enhance the therapeutic effect of the active ingredients of various drugs to promote drug absorption and solubility. It is known as a safe carrier for drugs. Excipients also help Used to give pills a uniform consistency.
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